I see benefits in choosing either one of them.
Beethoven's E Minor: Yes, there's that 10th stretch problem in the 2nd theme of the 1st movement, but it's a broken chord. So if you have a good wrist rotation (i.e. using your middle finger almost like a pivot), you can still play it even if your hand can't stretch that wide. For the 2nd movement, the right hand has a lot of voicing work--the outer fingers need to be able to sing and sustain the melodies.
Mozart's K 330: Don't underestimate this little gem. It's too easy to overshadow M.'s Sonatas by his Piano Concertos, which, I'll admit, are awesome masterpieces. But it takes a great deal of skills to bring out all the subtleties in K 330--things change so fast in this Sonata. You need really good articulation and good fingers to do justice all the ornaments. You also need a superb sense of rhythm.
Either one will make you a better musician!