As far as I understand, many instruments have a "home key" which is easier to finger than others (violins in G and carlinets in Eb), but since the keyboard is very roughly the same to play in every key, why do composers use other keys?
I can play in most keys, but I will shy away from pieces written in keys with --say-- 5 or 6 sharps or flats. Some of the hardest scores to play are in a "nominal" key (in the signature) but the measures are just peppered with accidentals, to include double sharps and double flats.This is very true of some pieces by Edward MacDowell.
due to the fact that there is by defintition a lowest pitch A
Certain piano sonorities are only possible in certain keys, due to the fact that there is by defintition a lowest pitch A on the (normal) instrument.