Many Europeans have a second, third and fourth finger much longer than their thumbs. Look at the vidoes of V. Horowitz, for example, his third finger is incredible. If your third finger is that long, you have to curl it up massively to use it and the thumb alternately. Most classical repretoire has fingering suggestions annotated first in Europe. Mr. Horowitz looks Prussian/white Russian to me, physically.
By contrast, my fingers aren't that much longer than my thumbs, so i use my thumbs a lot more than the fingering suggestions. My bone structure derives much more from my Native American (ie Siberian) ancestors than the European ones. Using the thumb is not hard for me.
But, in that measure I use the 2-4 span in the right hand. It's not more difficult really. You have to make a jump to get there, just which jump you use is important to be consistent. The important thing really memorizing is to be consistent in fingering.
I lost my JSB Inventions book (Schirmer Busoni ed) when I was in the Army, and when I went back to them in my late fifties I had a hard time picking up things I already knew because my fingerings weren't written in the new book. I wrote in some "new" fingerings, but found as the piece came back to me my brain went back to the old 40 year old fingerings. So I erased the pencil and wrote the old ones back int. #8 is one of my favorites, I play it several times a week.