Marijuana is by far the safest drug out there. Anybody with any expierence in the real world will tell you this.
The fact it is illegal is, without doubt, something that currently makes it unsafe in variety of "real world" ways. Completely irrespective of whatever its short or long-term effects on the human body are.
Irrespective of whether something should be or shouldn't be illegal, once it is, ignoring that and the potential consequences isn't wise.
I think most of the negative effects of drugs relate directly or indirectly to their legal status. Alcohol has been illegal in places in the past and I think the effects weren't disimilar.
We seem to live in societies that want to ban and control things all the time, even those that are pro- things need it to be harmless [perhaps partly because of that]
It's illegality and the potential consequences make it unsafe enough for me today. YMMV, but I wouldn't ignore it even if you don't agree with it.
I think if you choose to use it then you need to take a leaf [excuse the pun] out of the cigarette smoker's book and see that kidding yourself in the face of evidence to the contrary is just that, kidding yourself.
Of course, you need "evidence" - the place to get that probably isn't the pro- or anti- camps which are largely media and political points of view. Each will, if it uses studies, take the studies and media stories that fit their pov.
There are studies that link affected dopamine production with dope and there are those that don't. Take your pick

I doubt it will ever be legal. It's not technically legal in Amsterdam. In light of the law suits and whatnot against tobacco companies and the current shift from the battle against cigarette smoking [largely won, cannabis is dead from a "stick it in cigarettes" pov] towards alcohol [which you are fueling here] and fast food [which others have fueled with everything from meat to sugar becoming "poison" these days] I can't imagine who would want to sell the product anyway.
["you" doesn't refer [another bad pun] to anyone in particular]