beethovens last 5 sonatas are his hardest. the last 3 he wrote when he was deaf so it was more of a pure music thing and less pianistic, since he was deaf, he just left learning it up to the performer. Op.110 in my opinion is the easiest of the last 5-though it has a very difficult fugue.
Op.2 no.2, being one of his earlier sonatas, being more pianist and less technically challenging, the early sonatas also resembled classical style and tradition, as apposed to his later sonatas (including 110) which resembled a romantic style with a little bit of beethovens own ideas.
to the point, I personally like op.110 better than op.2 no.2. If your willing to put in a bit of extra work then do op.110 as I think it would be a more rewarding work. For less work you could also learn the also great op.2 no.2 which wouldn't be more like a haydn sonata and not as technically challenging.
All-and-all, I think it's just a matter of personal preference.
Good luck!