I'm assuming we're talking about the sustain pedal -- far right?
I do look at them -- provided that I am reasonably certain that they represent the composer's intentions, and not some arranger's ideas. One does have to be a little careful of that. What I am looking for is intention, though, and not necessarily an exact indication. The question is, did the composer intend the notes to continue sounding after the marked duration or didn't he (or she)? And sometimes the results are a little surprising...
I do not, however, follow the markings slavishly! Where there is a difference, though, it is usually that I may use a very brief pedal to make a better legato (my technique isn't all it might be, and I cheat) or I may use it on occasion for a fuller sound (hard to explain) on certain chords or notes.
As faulty said, the best rule is what sounds best in your specific situation -- but, particularly if you are self-taught, making this judgement call as to style of the piece can be tricky.