Where the heck did you get that score from??? PLEASE tell me it was NOT musescore...
Rather depends on the morphology and size of your hands as well as the action of your instrument. I take your point about the ring finger on the 2nd chord. I don't see anyway around this, but it wouldn't prove problematic to a good pianist. A weak 4th finger is more likely to hinder those who haven't got a few years practise under their belts. It gave me no problems and I am pretty crap. Thal
Those second and third chords are pretty gnarly.The only way I can figure out how play them is almost "diving" from above, like into a swimming pool, with the tips of my fingers "landing" pretty close to the fallboard.I wouldn't be able to play these at a fast tempo, or at least not easily.The short answer is: for me, it's rather uncomfortable. But I probably wouldn't be enraged enough to take a black felt pen and scribble vulgarities across the notes on the score.However, I'm not any great pianist: sort of middle-of-the-pack, at best. Good but limited in some ways.
I personally don't find the chords uncomfortable. As thalbergmad says, it depends a lot on your hand morphology.If you can reach the notes, maybe try and play it with a slight clenching motion (idk how else to describe it). Your wrist goes slightly higher and forward while playing it, without any tension in the hand. Imagine the cartwheel that you would do with your hand if you wanted to play C#-G#-C#-G# in quick succession.But it will only be really effortless if you have the hand size and structure for it. In addition to having reasonably large hands, you will need to be able to have enough space between the ring finger and pinky, especially in the left hand for the second chord.
I don't mind people writing music, it's just Musescore has a reputation of people putting up incredibly dodgy arrangements of other peoples music. I once saw a piece of music with like 15 leger lines in treble clef. It's not the music itself. I just hate Musescore because you'll get students who want to play pieces which they get for free, usually in the wrong time signature and not starting on the right beat or with the right key signature either. As a teacher, it's a pain in my arse.